Pharma giant Eli Lilly is creating 300 jobs in Limerick.
500 others will also be recruited during the construction phase of a major new investment.
The firm is spending 400 million euros on its high-tech factory which will manufacture injectable medicines.
Senior Vice President with Eli Lilly, Darin Moody, says Limerick was chosen ahead of other global locations.
Eli Lilly and Company is an American pharmaceutical company with its headquarters in Indianapolis and offices in 18 countries.
Its products are sold in approximately 125 countries.
The company was founded in 1876 by, and named after, Colonel Eli Lilly, a pharmaceutical chemist and veteran of the American Civil War.
The company has a forty-year history of manufacturing medicines in Ireland.
Access to university graduates, a skilled and english speaking workforce were some of the reasons Moody cited for Limerick being chosen.
