New Munster out-half Joey Carbery will start the first of Ireland's three-test tour in Australia.
Head coach Joe Schmidt has made a number of changes to his last team that played England in the 6 Nations on St Patrick's Day.
It's an all new front-row, with Rob Herring starting in place of the injured Rory Best at hooker, alongside Jack McGrath and John Ryan.
James Ryan and Iain Henderson make up the second row while, amid reports of injury concerns, Dan Leavy makes way for the Ulster-bound Jordi Murphy in the back-row, where he's joined by captain Peter O'Mahony and CJ Stander.
Conor Murray starts alongside Carbery in the half-back pairing, with Johnny Sexton starting from the bench.
Robbie Henshaw has recovered from injury to take his place at outside centre in place of Garry Ringrose, with Connacht's Bundee Aki inside him.
Finally, the back 3 line-up as it was during the Six Nations, with Jacob Stockdale and Keith Earls playing alongside full-back Rob Kearney.
Here's your Ireland team to play in Brisbane on Saturday.— Irish Rugby (@IrishRugby)