In the past, Britney Spears has danced with a snake, Christina Aguilera kissed Madonna and Beyoncé revealed her pregnancy live on-stage.
So what could possibly happen at this year's MTV Video Music Awards?
Cardi B - the woman with the most VMA nominations - is set to open the evening, after she stole the show with her performance of 'Bodak Yellow' last year.
Joining her on the line-up is the likes of Post Malone, with a rumoured special guest, Shawn Mendes, who's set to perform 'In My Blood', and Ariana Grande is taking to the stage with 50 diverse female dancers to smash 'God is a woman'.
Check out the full list of performers...
"It's most definitely a career milestone." - @JuiceWorlddd spoke to @MTVNews about his collabs with @TrvisXX and @1future— Video Music Awards (@vmas) August 19, 2018
Get ready for his performance on the #VMA PUSH Artist Stage
😈TOMORROW😈9p on @MTV pic.twitter.com/TTODKOE68v
"It's like a double blessing." @JLo reflects on being both nominated at the @VMAs and accepting the Video Vanguard Award.— MTV (@MTV) August 20, 2018
Don't miss her EPIC performance TONIGHT at the 2018 #VMAs at 9p on MTV. 💎 pic.twitter.com/BKzFzcfN9v
ICYMI #Barbz, your 👑QUEEN👑 @NICKIMINAJ answered some of the sweet and wild comments you all leave her on Instagram photos ✨— MTV (@MTV) August 19, 2018
Don't miss her performance at the 2018 #VMAs tomorrow at 9p 💫 pic.twitter.com/CT0eZRzw6h